Determination of ronidazole in pig and turkey feeding stuffs by gas-liquid chromatography

Abstract

A gas-liquid chromatographic method with flame-ionisation detection has been developed for the determination of ronidazole in complete feeding stuffs. The method is based on the formation of a volatile silyl derivative of ronidazole by reaction with NO-bis(trimethylsilyl)acetamide. Recoveries of ronidazole at the level of 60 mg kg^–1 were about 95%. No interference was observed from grass meal, fish meal or other drugs.