Issue 15, 1976
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Syntheses based on 1,2-secopenicillins. Part II. Preparation of 4-(3-substituted prop-2-ynylthio)azetidin-2-ones

Michael A. Harris,   Ian McMillan,   John H. C. Nayler,   Neal F. Osborne,   Michael J. Pearson  and  Robert Southgate  

Abstract

Treatment of benzyl 6β-(triphenylmethylamino)penicillanate with 3-substituted prop-2-ynyl bromides in the presence of strong base gave 1,2-secopenicillanates, which on permanganate oxidation afforded (3R,4R)-4-(3-substituted prop-2-ynylthio)-3-(triphenylmethylamino)azetidin-2-ones.

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Article information

DOI
https://doi.org/10.1039/P19760001612
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1976, 1612-1615

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Syntheses based on 1,2-secopenicillins. Part II. Preparation of 4-(3-substituted prop-2-ynylthio)azetidin-2-ones

M. A. Harris, I. McMillan, J. H. C. Nayler, N. F. Osborne, M. J. Pearson and R. Southgate, J. Chem. Soc., Perkin Trans. 1, 1976, 1612 DOI: 10.1039/P19760001612

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