Oxygen-18 and deuterium isotope effect on the freezing-point of dilute water + dioxan solutions

Abstract

Freezing points of dilute H₂¹⁶O, D₂¹⁶O and H₂¹⁸O + dioxan solutions were measured by equilibrium technique in the concentration range 0.03 to 0.8 mol kg^–1. No isotope effect on the association factor of water was found within the precision of the measurements, estimated as being about ±2.5 %, therefore the anomalously low dimerization constant of H₂¹⁸O earlier reported in the literature must be due to some experimental error.