Issue 23, 1976

Exceptionally easy isomerization of acetylenic alcohols with potassium 3-aminopropylamide. A new, high yield synthesis of functionally differentiated αω-difunctional structures

Abstract

Potassium 3-aminopropylamide, readily prepared in situ from KH and 3-aminopropylamine, effects rapid, multipositional isomerization of the triple bond in prop-2-ynylic and other acetylenic alcohols to the chain terminus remote from the hydroxy function, within minutes at 0–20 °C.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1976, 959-960

Exceptionally easy isomerization of acetylenic alcohols with potassium 3-aminopropylamide. A new, high yield synthesis of functionally differentiated αω-difunctional structures

C. A. Brown and A. Yamashita, J. Chem. Soc., Chem. Commun., 1976, 959 DOI: 10.1039/C39760000959

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