16β,18-Dihydroxylation of oxygenated 5α-androstanes with the fungus Leptoporus fissilis
Abstract
Incubation of certain dioxygenated 5α-androstanes, notably 3,6-hydroxy-ketones, with Leptoporus fissilis gives 16β, 18-dihydroxy- and 16β-monohydroxy-products in combined yields of over 50%.
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