A new high-yield procedure for the oxidation to oxindoles of 3-substituted indoles, including tryptophan-containing peptides and proteins, involving the use of a mixture of dimethyl sulphoxide and concentrated HCl, is described.
W. E. Savige and A. Fontana, J. Chem. Soc., Chem. Commun., 1976, 599 DOI: 10.1039/C39760000599
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