Issue 18, 1975

Alkoxide ion vs. methylthiolate ion displacement in the Grignard reaction on O-alkyl S-methyl phenylphosphonothiolate

Abstract

MeMgI reacts with O-alkyl S-methyl phenylphosphonothiolates to displace either the methylthio group with retention of configuration at phosphorus or the alkoxy group with inversion, the competition depending on the nature of the alkoxy group.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1975, 753-754

Alkoxide ion vs. methylthiolate ion displacement in the Grignard reaction on O-alkyl S-methyl phenylphosphonothiolate

K. E. Debruin and D. M. Johnson, J. Chem. Soc., Chem. Commun., 1975, 753 DOI: 10.1039/C39750000753

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