A short synthesis of (+)-isophyllocladene and (+)-phyllocladene

Abstract

Rearrangement of the ketone (4) obtained by photochemical cycloaddition of allene to Δ⁸⁽¹⁴⁾-podocarpen-13-one (5) leads to (+)-Δ¹⁵-isophyllocladen-14-one (3), which can be converted into (+)-isophyllocladene (2) or (+)-phyllocladene (1).