The benzylidene thiolactone rearrangement: a synthesis of 2-aryl-2,3-dihydrobenzo[b]thiophen-3-carboxylic acids
Abstract
Benzylidene derivatives of benzo[b]thiophen-2-one undergo base-catalysed ring opening and reclosure to produce high yields of 2-aryl-2,3-dihydrobenzo[b]-thiophen-3-carboxylic acids.