Nitration of 3-iodoanisole and 2,6-dimethyl-4-iodoanisole
Abstract
Nitration of 3-iodoanisole in the presence of nitrous acid was found to give 3-nitroanisole, 3-iodo-4-nitroanisole, and 3,6-di-iodo-4-nitroanisole. Nitration of 2,6-dimethyl-4-iodoanisole was found to result in the displacement of iodine. The rate of reaction was studied as a function of nitrous acid concentration and acidity. The results confirm the mechanism for nitrodeiodination proposed previously.