Amino-acids and peptides. Part XV. Syntheses of four tetrapeptides containing tyrosine and glycine residues
Abstract
Four tetrapeptides, Tyr-Gly-Gly-Tyr, Tyr-Gly-Tyr-Gly, Gly-Tyr-Gly-Tyr, and Gly-Tyr-Tyr-Gly, together with intermediate dipeptides, have been synthesised using the o-nitrophenylthio-group for N-protection and NN′-dicyclohexylcarbodi-imide–2,4,5-trichlorophenol for coupling reactions.