Homolytic aromatic substitution by heterocyclic free radicals. Part IV. Reaction of 5-substituted thiazol-2-yl radicals with alkylbenzenes

Abstract

The relative rates and the partial rate factors of the homolytic thiazolylation of alkylbenzenes by the thiazol-2-yl radical substituted in the 5-position by methyl, bromo, and nitro groups are reported. The radicals were generated by the aprotic diazotization of the corresponding 2-aminothiazoles. The results show a very small substituent effect compared with that observed for substituted phenyl radicals.