Synthetic studies related to nuclear analogues of the penicillins and cephalosporins
Abstract
A route developed for the synthesis of nuclear analogues of the penicillins and cephalosporins has been used to generate 2,2-dimethyl-8-oxo-7β-phenylacetamido-4-thia-1-aza-6αH-bicyclo[4·2·0]octane-3-carboxylic acid (17; R = H).