Synthesis of 4-amino-1H-1,5-benzodiazepine-3-carbonitrile and related compounds
Abstract
In the presence of hydrochloric acid, o-N-(2,2-dicyanovinyl)aminoaniline is easily converted into 4-amino-1H,1,5-benzodiazepine-3-carbonitrile, which can be hydrolysed with various bases to other diazepine, triazepine, or benzimidazole derivatives.