The aromatization of some 2α,3α-epoxy-5α-hydroxy-steroids
Abstract
2α,3α-Epoxy-5α-hydroxyandrostan-17-one and the corresponding 17β-acetate rearrange in hydrogen bromide-glacial acetic acid to form 4-methyloestra-1,3,5(10)-trien-17-one and the corresponding 17β-acetate. The related 6,17-diones afford 1-methyloestra-1,3,5(10)-triene-6,17-dione and the corresponding 17β-acetate.