Coproporphyrin-III from protoporphyrin-IX
Abstract
Manipulation of the vinyl side-chains of the readily available protoporphyrin-IX dimethyl ester (2) allows the synthesis of coproporphyrin-III tetramethyl ester (1) in an overall yield of 37%.
Manipulation of the vinyl side-chains of the readily available protoporphyrin-IX dimethyl ester (2) allows the synthesis of coproporphyrin-III tetramethyl ester (1) in an overall yield of 37%.
G. W. Kenner, S. W. McCombie and K. M. Smith, J. Chem. Soc., Chem. Commun., 1972, 1347 DOI: 10.1039/C39720001347
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