Reaction of the cytosine ring system with trifluoromethyl hypofluorite followed by decomposition of the resulting adduct gives the first direct synthesis of 5-fluorocytosine and selected 5-fluorocytosine nucleosides in good yields.
M. J. Robins and S. R. Naik, J. Chem. Soc., Chem. Commun., 1972, 18 DOI: 10.1039/C39720000018
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