The configuration of 1α-methyl-5α-androstan-3-ones
Abstract
The α-configuration of the 1-methyl group in 1α,17α-dimethyl-17β-acetoxy-5α-androstan-3-one has been unambiguously confirmed (a) by dehydrogenation with 2,3-dichloro-5,6-dicyanobenzoquinone, and (b) by use of the paramagnetic shift reagent trisdipivalomethanatoeuropium(III). Ring A has been shown to possess a chair conformation.