The two stereoisomeric 2-(6-methoxy-2-naphthyl)-1-methyl-5-oxocyclopentane-1-acetic acids have each been reduced to a lactone and a hydroxy-acid. These products have been further reduced to give the four corresponding (±)-hydroxyethylcyclopentanols required for biological evaluation. A number of related diols have also been prepared for comparison.
E. G. Brain, F. Cassidy, M. F. Constantine, J. C. Hanson and D. J. D. Tidy, J. Chem. Soc. C, 1971, 3846 DOI: 10.1039/J39710003846
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