Pyrazolopyrimidine nucleosides. Part I. Synthesis of pyrazolopyrimidine nucleosides related to the nucleoside antibiotic tubercidin
Abstract
A new route for the preparation of 4-amino-1-(β-D-ribofuranosyl)pyrazolo[3,4-d]pyrimidine (5)(6-azatubercidin) is described. The anomeric configuration of the product has been established unequivocally for the first time by cyclonucleoside formation, and agrees with previously reported anomeric assignments.