Issue 24, 1971

The NIH shift during the hydroxylation of aromatic substrates by fungi

Abstract

The migration and retention of deuterium which occurs during aromatic hydroxylation of several substrates (NIH Shift) with a range of fungi is compared to the migration and retention obtained with liver microsomes and a chemical model system; enzymatic mechanisms are discussed in terms of arene oxide intermediates.

Article information

Article type
Paper

J. Chem. Soc. D, 1971, 1585-1587

The NIH shift during the hydroxylation of aromatic substrates by fungi

B. J. Auret, D. R. Boyd, P. M. Robinson and C. G. Watson, J. Chem. Soc. D, 1971, 1585 DOI: 10.1039/C29710001585

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