Issue 15, 1971

Total synthesis of a nuclear analogue of the penicillin–cephalosporin antibiotics

Abstract

A synthetic route has been developed for the preparation of nuclear analogues of the penicillin–cephalosporin group of antibiotics and is illustrated by the synthesis of (2R,6R,7S)-8-oxo-7-phenylacetamido-1-azabicyclo[4,2,0]octane-2-carboxylic acid (17) from D-pipecolic acid.

Article information

Article type
Paper

J. Chem. Soc. D, 1971, 865-867

Total synthesis of a nuclear analogue of the penicillin–cephalosporin antibiotics

D. M. Brunwin, G. Lowe and J. Parker, J. Chem. Soc. D, 1971, 865 DOI: 10.1039/C29710000865

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