The determination of nikethamide and other compounds in pharmaceutical dosage forms by thin-layer chromatography

Abstract

The qualitative examination and quantitative assay of pharmaceutical dosage forms containing nikethamide by thin-layer chromatography is described. When applicable, the determination of accompanying active compounds such as adenosine, caffeine, strychnine and theophylline by the same method is also described. Individual quantitative determinations of the eluted drugs are performed by ultraviolet spectrophotometry.