X-Ray analysis of the structure of (±)-1-acetyl-3-methylaspidospermidine 9-methiodide

Abstract

The structure of (±)-1-acetyl-3-methylaspidospermidine 9-methiodide was determined. The crystals are triclinic, space group P, cell constants a= 16·21, b= 14·53, c= 11·08 Å, α= 102·10, β= 108·05, γ= 102·75°, Z= 4. The structure was solved by the heavy-atom method and refined isotropically to R= 12·8%. The conformation of the two enantiomorphic molecules in the asymmetric unit is discussed in detail and compared with that of related compounds for which torsion angles were calculated by use of co-ordinates reported in the literature.