Synthesis of erythro-18,19-dihydroxysqualene 2,3-oxide and other internally oxidized squalene derivatives
Abstract
In addition to the title compound, the preparation of the four possible internal monodiols and of the four possible internal monoepoxides of squalene are described; trisubstituted aliphatic epoxides were found to be readily deoxygenated by zinc dust/acetic acid.