Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

There will be scheduled maintenance work beginning on Saturday 15th June 2019 at 8:30 am through to Sunday 16th June 2019 at 11:30 pm (BST).

During this time our website may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 0, 1970
Previous Article Next Article

The reactivity of phosphate esters. Diester hydrolysis

Abstract

Phosphate diesters are, in general, exceedingly unreactive compounds, but their reactivity towards hydrolysis depends strongly on the basicity of the leaving group. As a result the difference in reactivity between diester and monoester monoanions decreases rapidly as the basicity of the leaving group decreases, and with very good leaving groups the reactivity of the two classes of compounds is comparable. The mechanism of hydrolysis of phosphate diester anions appears to involve bimolecular nucleophilic attack of solvent on phosphorus.

Back to tab navigation

Article type: Paper
DOI: 10.1039/J29700000510
J. Chem. Soc. B, 1970, 510-513

  •   Request permissions

    The reactivity of phosphate esters. Diester hydrolysis

    A. J. Kirby and M. Younas, J. Chem. Soc. B, 1970, 510
    DOI: 10.1039/J29700000510

Search articles by author

Spotlight

Advertisements