Peptides. Part XXIX. Synthesis of canine gastrin and a new synthesis of human gastrin
The heptadecapeptide amide [graphic omitted]lu-Gly-Pro-Trp-Met-Glu-Glu-Ala-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2(canine gastrin I) has been synthesised by a new general route, and the [Leu5,Glu8]-analogue (human gastrin I) by a variant of it. O-Acylation of tyrosine derivatives by N-hydroxysuccinimide esters was found to occur in aqueous but not in anhydrous solution.