Condensation of 4-methylpentan-2-one with dimethyl dimethylmaleate by use of sodium hydride gives calythrone (2-isovaleryl-4,5-dimethylcyclopentene-1,3-dione)(ca. 5%) but the main product is an ester, shown to be methyl 4-isovaleryl-2-methyl-3-oxocyclopentanecarboxylate and not as previously suggested. Reactions with acetone and acetophenone give only the corresponding cyclopentanone derivatives.
M. Elliott, N. F. Janes and K. A. Jeffs, J. Chem. Soc. C, 1969, 1845 DOI: 10.1039/J39690001845
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