Comparison of field and σ-inductive models for the transmission of nonconjugative substituent effects. The 2,6-spiro[3,3]heptyl system
Abstract
The pKa values of a series of 6-substituted spiro[3,3]heptane-2-carboxylic acids have been measured in 50%(by wt.) aqueous ethanol and the results analysed in terms of the mechanism of transmission of nonconjugative substituent effects.