Steroids. Part II. Deamination of 5α-amino- and 6α-amino-5β-hydroxy-steroids
Abstract
Aprotic deamination of 3β,6β-diacetoxy-5α-aminocholestane gave a Westphalen rearrangement in which an increased ratio of Hofmann to Saytzeff product is obtained. Deamination of 6α-aminocholestane-3β,5β-diol gave 3β-hydroxy-A-homo-B-nor-5β-cholestan-4a-one.