Studies on bicyclononanes. Part V. Formation of substituted bicyclononanes from enamines
Abstract
The reaction of the enamines of 4-alkylcyclohexanones with acraldehyde, of cinnamaldehyde with 1-morpholinocyclohexene, and a stereospecific synthesis of cis-3-methylcyclo-octanol are described. The reaction of a cyclohex-3-enyl halide with a Grignard reagent is shown to lead to axial products. An explanation is proposed for the steric course of certain Michael additions.