Arylazo-steroids. Part III. 3-, 7-, and 17-Arylazo-steroids

Abstract

A number of 3-arylazo-5α- and -5β-cholestanes have been synthesised, and also their 3-hydroperoxy-derivatives. The previously described 17-phenylazoandrost-5-en-3β-ol has been shown to have the 17β-configuration, and a number of derivatives with 17 α-substituents have been synthesised. The preparation of a 7-hydroperoxy-7-phenylazo-5α-cholestan-3β-yl acetate is described. The ultraviolet and visible spectra of the above compounds are discussed. Comment is made on the reduction of phenylhydrazones with lithium aluminium hydride.