Humulone and isohumulone are each oxidised using monoperphthalic acid to give 5-(2,3-dihydroxy-3-methylbutyl)-4-(3,4-epoxy-4-methylpentanoyl)-3,4-dihydroxy-2-isovalerylcyclopent-2-en-1-one. This product is a constituent of the hard resin fraction of hops.
B. E. Connett and J. A. Elvidge, J. Chem. Soc. C, 1968, 1193 DOI: 10.1039/J39680001193
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