Kinetics of the reversible addition of water to substituted quinazolines and some triazanaphthalenes
Abstract
A rapid-reaction technique has been used to study the pH-dependence of the reversible addition of water across the 3,4-double bond of some substituted quinazolines and 1,3,5-, 1,3,7-, 1,3,8-, and 1,4,6-triazanaphthalene. The pH–rate profiles for the hydration and dehydration reactions have been calculated from the observed pseudo-first-order rate constants. Substituent effects are discussed.