Open Access Article
This Open Access Article is licensed under a Creative Commons Attribution 3.0 Unported Licence
Expression of concern: The design and synthesis of redox-responsive oridonin polymeric prodrug micelle formulation for effective gastric cancer therapy
Luzhou Xua,
Lei Zhua,
Kai Zhenga,
Junlou Liub,
Panpan Tianc,
Di Hub,
Qianqian Wangb,
Qiaoyun Zuob,
Xiaosong Ouyangb,
Yanna Daib,
Yuxian Fub,
Xinyi Daib,
Fang Huang*d and
Jun Cheng*ef
aGastroenterology Department, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China
bThe First Clinical Medical College of Nanjing, University of Chinese Medicine, Nanjing, 210023, China
cInternal Medicine Department, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China
dSchool of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing, 211199, China. E-mail: chengtianle007@163.com
eJiangsu Hongdian Research Institute of Traditional Chinese Medicine Industry, Nanjing, 210042, China. E-mail: cj9119@sina.com
fNanjing Zhongshan Pharmaceutical Co. Ltd, Nanjing, 210046, China
First published on 10th December 2025
Abstract
Expression of concern for ‘The design and synthesis of redox-responsive oridonin polymeric prodrug micelle formulation for effective gastric cancer therapy’ by Luzhou Xu et al., J. Mater. Chem. B, 2021, 9, 3068–3078, https://doi.org/10.1039/D1TB00127B.
The Royal Society of Chemistry is issuing this notice to alert readers that since the publication of this manuscript, BGC 823 and SGC 7901 cell lines have been identified as potentially contaminated and/or unverifiable.1 This may reduce the specific relevance of these results to gastric cancer.
Michaela Muehlberg
20th November 2025
Executive Editor, Journal of Materials Chemistry B
References
- D. J. Oste, P. Pathmendra, R. A. K. Richardson, G. Johnson, Y. Ao, M. D. Arya, N. R. Enochs, M. Hussein, J. Kang, A. Lee, J. J. Danon, G. Cabanac, C. Labbé, A. C. Davis, T. Stoeger and J. A. Byrne, Int. J. Cancer, 2024 DOI:10.1002/ijc.34995.
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