Open Access Article
Vicente Talanquer
Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85745, USA. E-mail: vicente@arizona.edu
First published on 19th December 2025
Persistent difficulties in students’ ability to apply chemical knowledge across contexts suggest limits not to memory but of cognitive flexibility. This paper argues that such flexibility depends on conceptual reframing, understood as the capacity to reinterpret a phenomenon through alternative disciplinary lenses, which in this study take the form of distinct conceptual lenses within chemistry. Drawing on insights from cognitive flexibility theory, epistemic cognition, and philosophy of science, I propose that chemistry's inherently pluralistic structure requires learners to navigate among multiple legitimate modes of reasoning. I describe conceptual reframing as the cognitive process that enables this navigation and link it to mechanisms of context-sensitive activation and conceptual coordination. Building on existing ideas in science and chemistry education, I present curricular and pedagogical suggestions that emphasize recursive, phenomenon-based learning and metacognitive engagement with framing choices. Illustrative examples, such as the teaching of acid–base chemistry, demonstrate how instruction can foster conceptual reframing and knowledge transfer across contexts. Cultivating such pluralistic reasoning, I argue, is key to preparing learners to think adaptively, critically, and reflectively in a complex, interconnected world.
In this essay, I argue that an important contributor to this problem is the limited cognitive flexibility that traditional chemistry instruction fosters in students. Cognitive flexibility refers to the capacity to reorganize and adapt one's conceptual and representational understanding across different contexts (Spiro et al., 2017; Braem and Egner, 2018). I propose that conceptual reframing—defined as the ability to reinterpret a phenomenon or problem through alternative disciplinary lenses, which in this study correspond to distinct conceptual lenses within chemistry—is essential for enabling meaningful knowledge transfer in chemistry (Hammer et al., 2005; Slominski et al., 2020). Conceptual reframing represents the cognitive process that allows experts to move fluidly among different ways of thinking, both across and within disciplines, a capacity grounded in what philosophers of science describe as conceptual pluralism (Bensaude-Vincent and Simon, 2008; Chang, 2014; Schummer, 2015; Bélanger et al., 2023a, 2023b): the recognition that disciplinary knowledge is structured through multiple, sometimes compatible and sometimes incompatible conceptual frameworks, each capturing different aspects, levels, or goals of understanding.
Chemistry as a discipline is inherently pluralistic (Ruthenberg and Mets, 2020). The same phenomenon can be represented through distinct theoretical frameworks (quantum versus classical descriptions of particle motion), conceptual models (valence bond versus molecular orbital theories), mechanistic accounts (structural versus kinetic explanations), or analytical perspectives (for example, the effect of proton transfer on solution pH versus chemical reactivity). Expert chemists routinely navigate and integrate these perspectives depending on their explanatory or predictive goals. In contrast, students typically encounter them as disconnected bodies of knowledge, each confined to a course, topic, or textbook chapter. As a result, they are seldom taught how to reframe a concept productively when the context, scale, or explanatory goal changes.
Addressing this challenge requires both curricular and pedagogical innovation. Instruction should create systematic opportunities for students to recognize diverse conceptual and analytical emphases, to articulate how different models and explanations serve distinct purposes, and to practice transferring ideas across representational and contextual boundaries (Nehring and Schanze, 2025). Fostering conceptual reframing is therefore not simply a matter of improving knowledge retention, but of cultivating the cognitive flexibility that underlies expert chemical thinking.
These four forms of pluralism shape the epistemic landscape of chemical thinking. They illustrate that chemistry is not a single, unified way of reasoning but a network of interrelated frameworks that operate across scales and purposes (Chang, 2014; Schummer, 2015). Chemists navigate among these frameworks according to the scale, purpose, and computational demands of the problem. However, this navigation is often influenced by disciplinary norms, prior knowledge, experience, and individual preferences rather than by intentional and exhaustive use of all available lenses. For experts, this pluralism is productive: it supports flexible shifting among perspectives, selective integration of insights, and creative application of knowledge. For students, however, it can be a source of fragmentation if they are not explicitly taught how these perspectives relate and when each is appropriate.
The four forms of pluralism described above can be contrasted along their epistemic focus, degree of compatibility, and implications for learning as summarized in Table 1. Together, they illustrate the multiple conceptual terrains that chemists navigate when reasoning about chemical phenomena.
| Form of pluralism | Nature of the perspective | Level of reasoning | Typical examples | Relationship among frameworks | Implications for learning |
|---|---|---|---|---|---|
| Theoretical pluralism | Coexistence of alternative or complementary foundational frameworks that provide different ontological descriptions of chemical behavior. | Fundamental physical principles that govern matter and energy at different scales. | Classical vs. quantum mechanics | May be partially incompatible but valid in distinct domains of applicability. | Students must recognize boundaries of validity and conditions under which each theory applies. |
| Model pluralism | Use of multiple conceptual models or idealizations within a shared theoretical framework. | Representational structures used to explain or predict properties and behavior. | Valence bond vs. molecular orbital theory; Arrhenius, Brønsted–Lowry, and Lewis acid–base models. | Models overlap and can be integrated or selected depending on the task. | Instruction should emphasize the model's purpose, scope, and limitations. |
| Mechanistic pluralism | Existence of multiple causal narratives or levels of description for the same process. | Causal chains at different granularity levels linking structure, energy, and dynamics. | Electronic, structural, and kinetic accounts of chemical reactions. | Frameworks are complementary and can be integrated into multilevel explanations. | Learners benefit from connecting mechanisms across scales and identifying how causal levels interact. |
| Analytical pluralism | Adoption of different interpretive lenses according to the explanatory or practical goal. | Contextual framing of inquiry and choice of relevant variables and measures. | Interpreting proton transfer through effects on solution pH, reactivity, or speciation | Perspectives are context-dependent and chosen based on purpose. | Practice is needed in selecting and justifying appropriate lenses for different questions or applications. |
This example illustrates how a single chemical process can be understood through multiple theoretical, representational, mechanistic, and analytical frameworks. Recognizing proton transfer as a pluralistic construct underscores the need to help students learn how to reframe their understanding—to move flexibly among theories, models, mechanisms, and analytical lenses—depending on the problem at hand. Developing this ability requires that students not only learn individual theories, models, or mechanisms, but also recognize how each frames a phenomenon differently and reason across their boundaries.
Two related mechanisms appear central to this capacity. The first is context-sensitive activation, the ability to identify cues that signal which conceptual framework or model is most productive for interpreting a problem, and activate associated resources (Hammer et al., 2005; Wagner, 2006). The second key mechanism is conceptual coordination, the capacity to translate, align, reconcile, or integrate ideas across alternative conceptual frameworks and their associated representational systems (Markauskaite and Goodyear, 2017; Legare and Shtulman, 2018). This process involves aligning meanings that are expressed differently within distinct theoretical, model-based, mechanistic, or analytical lenses. For example, connecting a thermodynamic energy profile with a molecular orbital description of bond reorganization. In this sense, conceptual coordination entails representational coordination as a supporting process.
Both mechanisms rely on metacognitive monitoring and epistemic awareness: experts are conscious of the assumptions, scope, and purposes that define each framework and can shift deliberately when those boundaries are reached (Elby and Hammer, 2010; Hofer, 2018). These processes parallel the mechanisms of adaptive expertise when viewed as a distributed phenomenon (Martin and Dixon, 2024). In this perspective, adaptive expertise involves (1) the recruitment and coordination of resources (cognitive, representational, and social) needed to address a task; (2) the reframing of problems and goals, through which individuals redefine what counts as relevant knowledge or an appropriate explanation; and (3) navigational foresight, the anticipatory capacity to recognize when to shift frameworks or representations as conditions change. Conceptual reframing, therefore, constitutes the cognitive core of distributed adaptive expertise: it enables chemists to reorganize conceptual and representational resources dynamically, aligning them with evolving goals and contexts of reasoning.
For example, when the goal is to assess whether an electron-transfer process will occur spontaneously, a chemist activates a thermodynamic redox frame. In this frame, electron transfer is interpreted in terms of reduction potentials and Gibbs free energy change. Relevant representations include half-reactions, electrochemical series, and quantitative relationships between ΔG and cell potential. The focus is on energetic driving forces and macroscopic observables such as cell voltage.
If the problem shifts to understanding how electron transfer occurs at the molecular level, a different conceptual frame becomes salient. The chemist may activate a molecular orbital frame, conceptualizing electron transfer as the movement of an electron from a donor orbital to an acceptor orbital. Representations shift from electrochemical equations to energy-level diagrams and orbital overlap. The same electron-transfer event is now interpreted in terms of electronic structure and orbital symmetry rather than thermodynamic favorability alone.
Alternatively, the chemist may adopt a mechanistic electron-flow framework to analyze how electrons move through a reaction pathway. In this framing, electron transfer is represented using curved-arrow notation to track the redistribution of electron density across bonds and atoms during a reaction. This frame foregrounds causal reasoning about bond formation and bond breaking, intermediates, and transition states. It requires coordination between symbolic representations and structural features to explain how local electron movements give rise to observable chemical transformations.
In other contexts, however, a redox-accounting frame may be sufficient, in which oxidation states are used to identify which species is oxidized or reduced without invoking a mechanistic picture of electron motion. Or electron transfer may be inferred indirectly through compositional changes, such as shifts in hydrogen or oxygen content, which serve as empirical proxies for changes in electron density in many chemical and biochemical systems.
Across these shifts, context-sensitive activation enables the chemist to recognize which conceptual frame is appropriate given the problem's focus: reaction feasibility, electronic structure, mechanistic pathway, or electron accounting. Conceptual coordination allows the chemist to translate information across frames, for instance, by connecting a favorable reduction potential to a plausible orbital interaction, or by relating a change in oxidation state or composition to an underlying mechanistic process. Expert reasoning depends on maintaining coherence across these frameworks while flexibly reorganizing the conceptual relations each frame emphasizes.
This example illustrates that conceptual reframing involves more than recalling alternative concepts; it requires the controlled reorganization of conceptual and representational systems to serve different explanatory aims. The same chemical phenomenon is understood through distinct, internally coherent frameworks that must be selected and coordinated dynamically. The capacity to shift among these lenses underlies expert chemical reasoning and exemplifies the mechanisms that support adaptive transfer across contexts.
| Conceptual change | Conceptual reframing | |
|---|---|---|
| Focus | How learners move from intuitive to scientific understanding. | How learners move among multiple legitimate scientific frameworks. |
| Interest | Restructuring conceptual systems. | Developing the ability to flexibly activate and coordinate conceptual systems. |
| Mechanism | Inhibition of prior frame and activation of new one, guided by epistemic control. | Metacognitive selection, contextual activation, and alignment across frameworks. |
| Cognitive Goal | Coherence within a single framework. | Coherence across multiple frameworks. |
Conceptual reframing also provides a cognitive account of how transfer occurs in a pluralistic discipline. Traditional views of transfer often assume that knowledge acquired in one context is reapplied unchanged in another (Kaminske et al., 2020). In chemistry, however, such direct transfer is rarely possible because the same phenomenon may be described through different frameworks depending on the purpose of analysis (Mestre, 2005). Reframing allows experts to achieve adaptive transfer, understood as the reinterpretation and reconstruction of prior knowledge to fit new contexts or explanatory goals.
In this view, successful transfer is not a matter of retrieving the correct concept but of recontextualizing it within new conceptual and epistemic frames (Hammer et al., 2005). For example, an expert who understands proton transfer as atomic displacement in general chemistry can reframe the same process as an electronic reorganization in organic chemistry or as a regulatory mechanism in biochemistry. The underlying knowledge is related, but its conceptual organization and explanatory role change with the context. Conceptual reframing thus bridges local understanding and broader knowledge transfer by enabling learners to reinterpret rather than merely recall information.
Understanding reframing as the mechanism of adaptive transfer clarifies why students often struggle to apply prior knowledge: they may have learned individual frameworks but not how to navigate among them. Supporting this capacity requires instruction that makes the pluralistic nature of chemistry explicit and provides opportunities to practice reframing across contexts.
Curricula that prioritize breadth over depth often separate conceptual frameworks by topic, unit, or course, for example, treating quantum mechanics, equilibrium, and molecular structure as largely independent domains. Although students may encounter the same chemical phenomenon across courses, the associated conceptual lenses are typically introduced in isolation and without explicit comparison or coordination. As a result, students are rarely asked to examine how different frameworks offer complementary, and sometimes competing, accounts of the same process.
To foster conceptual reframing, curricular design must instead emphasize explicit, within-course recurrence and comparison of frameworks around shared phenomena, rather than relegating different lenses to different disciplinary contexts. Core chemical processes such as molecular bonding, proton transfer, and energy transformation should reappear within instructional sequences in the same course, with students intentionally prompted to reinterpret the same phenomenon through multiple conceptual lenses and to reflect on the affordances and limits of each (Adipat, 2024; Scharlott et al., 2024). This recursive, phenomenon-centered structure creates systematic opportunities for students to recognize how alternative models foreground different levels of description, representational systems, and explanatory goals.
A pluralistic curriculum, in this sense, organizes learning around problems that invite reframing rather than around topics to be covered. The key distinction from traditional approaches is not merely that students encounter multiple perspectives over time, but that they are asked to coordinate and contrast these perspectives in relation to the same chemical situation, developing epistemic control over when and why each framing is productive.
The teaching of acid–base concepts provides a concrete illustration of this distinction. Traditional instruction often emphasizes a single dominant frame within a given course. For example, quantitative pH calculations in general chemistry or mechanistic proton transfer in organic chemistry. While each approach is appropriate in context, treating them separately can obscure the broader role of proton transfer as a unifying chemical mechanism. A reframing-oriented curriculum instead invites students within a single course to analyze the same acid–base phenomenon from analytical, structural, and functional perspectives, making explicit how each lens supports different explanatory aims.
For example, in a general chemistry course, students might examine ocean acidification through an analytical lens, connecting atmospheric CO2 levels to changes in pH; analyze protonation effects on drug solubility and reactivity from an organic chemistry perspective; and consider how proton transfer modulates enzyme function in biochemical systems. Crucially, these analyses are not presented as independent applications, but as coordinated interpretations of a shared underlying process (e.g., proton transfer, electron transfer).
By making these framings explicit and connecting them through shared core concepts, such as energy change, electron redistribution, and molecular stability, students can come to see chemistry as an integrated yet context-sensitive discipline. This approach models expert practice not as the exhaustive use of all possible lenses, but as the selective and reflective deployment of conceptual frameworks aligned with specific explanatory goals.
Such integration can be reinforced through intentional, collaborative curriculum design within and across course boundaries, ensuring that core concepts are revisited and applied with different explanatory purposes. This reconceptualization is urgently needed to prepare students to address complex, real-world challenges, ranging from climate change to sustainable resource management, that demand analysis from multiple scientific perspectives.
Conceptual reframing should also be supported through instructional models that treat learning from a pluralistic perspective. For example, Potvin (2023) proposes that if scientific learning is viewed not as the replacement of intuitive ideas but as the dynamic competition and coordination among coexisting conceptions, instruction should be designed around iterative cycles of assimilation, discrimination, and automatization. Students must therefore encounter multiple conceptions, including those deemed “non-normative,” be guided to analyze their contextual usefulness, and be given multiple opportunities to apply targeted conceptions to strengthen automatization. Rather than eradicating intuitive ideas, instruction should help learners discriminate among them, recognize where each applies, and progressively increase the prevalence of scientifically productive frames. The same model can be extended to foster conceptual reframing, affirming conceptual plurality as a natural and essential feature of scientific reasoning.
Students’ ability to reframe concepts can be further developed through engagement in the discourse practices of each subdiscipline. Constructing explanations and building arguments about relevant phenomena from multiple frames (Berland and Reiser, 2009; Berland et al., 2020) helps students apply prior knowledge across diverse contexts, reinforcing conceptual integration. This approach is most effective when instruction throughout the chemistry curriculum is grounded in model-based reasoning that emphasizes particle- and molecular-level explanations (Teichert et al., 2017; Saba et al., 2023) and draws on general mechanisms shared across chemical domains (Talanquer, 2018), such as energy transfer, charge redistribution, and electron stabilization.
Finally, pedagogical practice must engage students in activities that promote metacognitive control over their own framing processes. Teaching for conceptual reframing means helping learners not only acquire chemical knowledge but also learn how to choose and coordinate conceptual lenses appropriate to a given problem. Several evidence-based strategies can support this goal:
• Explicit framing prompts. Teachers can help students recognize framing as an intentional act by asking questions such as, “Which conceptual lens applies here and why?” or “Would a kinetic or thermodynamic perspective better explain this phenomenon?” Such prompts externalize the process of context-sensitive activation and make epistemic choices visible.
• Comparative analysis tasks. Teachers can ask students to analyze the same phenomenon through multiple sub-frameworks. For example, considering a chemical reaction in energetic, structural, and mechanistic terms fosters discrimination among conceptual models and clarifies their complementary roles.
• Metaconceptual reflection. Students should be encouraged to articulate the boundary conditions and limitations of each framework (“When does this model stop working?”). This practice strengthens epistemic awareness and the capacity for deliberate reframing.
• Representation switching. Students should be given multiple opportunities to translate among symbolic, graphical, and verbal representations to reveal structural relations among models and develop the ability to preserve coherence across representational systems.
These strategies cultivate what Perkins (1998) called flexible performance: the ability to redeploy conceptual tools as the situation demands. They also parallel the “discrimination” and “inhibitive stop sign” phases in Potvin's (2023) conceptual prevalence model, where learners learn to recognize when one conception ceases to be useful and when another should be activated. Rather than framing learning as a confrontation between right and wrong ideas, such instruction presents it as a cognitive and epistemic choice among contextually valid alternatives (Louca et al., 2004; Hammer et al., 2005).
Such a perspective reframes chemistry learning itself not as the accumulation of stable truths, but as participation in the cognitive practices of the discipline. These practices require moving flexibly among frameworks, aligning representations, and evaluating their contextual utility. When curricula and pedagogy make this pluralism explicit, chemistry education can move beyond rote application toward cultivating learners who think and reason as adaptive, reflective participants in a pluralistic scientific community.
Supporting students in developing this capacity demands attention to the full range of factors that shape learning: cognitive and affective processes, curricular and pedagogical design, and the cultural and contextual conditions that influence students’ epistemic beliefs, values, and engagement with disciplinary practices (Talanquer et al., 2024; Talanquer and Kelly, 2024). As chemistry educators, we can begin by reflecting on how we ourselves frame core concepts across subdisciplines, and by making those framings visible to our students. Helping learners recognize, compare, and navigate among these perspectives will not only foster conceptual reframing but also prepare them to engage with science as a dynamic, pluralistic enterprise.
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