Access to α-carbonyl vinyl sulfoxonium ylides via Tandem rearrangement–addition of cyclic ethynylethylene carbonates

Abstract

We report here a copper-catalyzed reaction of sulfoxonium ylides with cyclic ethynylethylene carbonates, enabling efficient access to highly functionalized α-carbonyl vinyl sulfoxonium ylides. This transformation proceeds via nucleophilic addition of the ylide α-carbon to an unsaturated bond, demonstrating a broad substrate scope. Notably, it offers a practical route to densely substituted tetrasubstituted olefins while preserving the versatile ylide moiety, which can be further diversified through a range of downstream transformations.