Photoinduced deconstruction of cycloalkanols for site-selective sulfonylsulfination

Abstract

A facile methodology for photo-enabled ring-opening sulfonylsulfination of cycloalkanols is reported, providing direct access to valuable ketones bearing sulfone and sultine moieties with S^IV and S^VI centers under mild and sustainable conditions with broad functional-group tolerance. Mechanistic investigations suggest a PCET-mediated deconstructive process and a radical-polar crossover cyclization pathway involving double SO₂ insertion in this transformation.