Visible light-induced regioselective/dehydrogenative C–H silylation of (thio)chromones via a tricatalytic process

Abstract

Direct C–H silylation of (thio)chromones was achieved by the combination of hydrogen atom transfer (HAT), photoredox and transition-metal catalysis under ambient air conditions. High regioselectivity, oxidant- and noble-metal-free conditions, and synergistic multiple catalysis were the major features of this protocol. Moreover, this approach can be safely conducted on the gram scale with hydrogen as the sole byproduct.