Metal-free photocatalytic peroxy-pyridylation of alkenes

Abstract

A metal-free photocatalytic peroxy-pyridylation of alkenes with oxime ester and tert-butyl hydroperoxide as substrates is reported. Under visible-light irradiation, the protocol achieves simultaneous introduction of both a peroxy group and a pyridyl group across an alkene, with distinguished chemo- and regioselectivity. This process directly affords β-pyridyl peroxides in moderate to excellent yields and exhibits a broad substrate scope.