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Correction: A gut–brain axis on-a-chip platform for drug testing challenged with donepezil
Francesca Fanizzaa,
Simone Perottonia,
Lucia Boeria,
Francesca Donnalojaa,
Francesca Negroa,
Francesca Puglia,
Gianluigi Forlonib,
Carmen Giordano*a and
Diego Albanib
aDepartment of Chemistry, Materials and Chemical Engineering ‘Giulio Natta’, Politecnico di Milano, Milan, Italy. E-mail: carmen.giordano@polimi.it
bDepartment of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
First published on 20th March 2026
Abstract
Correction for ‘A gut–brain axis on-a-chip platform for drug testing challenged with donepezil’ by Francesca Fanizza et al., Lab Chip, 2025, 25, 1854–1874, https://doi.org/10.1039/D4LC00273C.
The authors regret an error in Fig. 10a, where the same image was used for both the gut and liver images. The figure has been corrected to:
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| Fig. 1 (a) Z-Stack projection of immunofluorescence confocal microscopy images of endothelial cells in the BBB OOCs in the perfused conditions; green = ZO-1 and blue = Hoechst nuclear staining. Magnification: 40×. Scale bar: 50 μm. White arrows show the direction of fluid flow. (b) Cell viability with respect to the untreated conditions (control) of endothelial cells in the gut, liver and BBB OOCs measured with the MTS assay. ns p > 0.05 Mann–Whitney test was conducted for each group compared to the respective non-treated control. | ||
In addition, the last sentence in the section “Evaluation of donepezil biologic effects on individual OOC of the platform”, beginning with “The endothelial cells in the…” is replaced with:
“The endothelial cells seemed to align along the direction of fluid flow, as evidenced by zonulin-1 (ZO-1) staining, and were viable as demonstrated by the MTS assay”.
An independent expert has viewed the corrected image and text, and has concluded that they are consistent with the discussions and conclusions presented.
The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.
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