Combined operando UV/vis and NMR spectroscopy gives mechanistic insight into the reaction of guaiazulene with 2,4-dinitrobenzaldehyde

Abstract

In this proof-of-principle study, we apply combined NMR and UV/vis spectroscopy to operando reaction monitoring of a ‘classical’ organic reaction. We show that identical intensity-vs.-time courses are obtained for an intermediate visible in both NMR and UV/vis, and propose a mechanism accounting for the dependence of the reaction on c(HPF₆).