A UiO-66-derived nano-separation microelectrode for in vivo dopamine sensing with high sensitivity and selectivity

Abstract

Inspired by the separation properties of metal–organic frameworks (MOFs), we develop a UiO-66-(COOH)2-functionalized electrochemical sensor for in vivo dopamine (DA) detection. It exhibits high sensitivity and selectivity, enabling in vivo monitoring of DA release in rat brains induced by the local microinjection of a carbon monoxide (CO) donor.

Graphical abstract: A UiO-66-derived nano-separation microelectrode for in vivo dopamine sensing with high sensitivity and selectivity

Supplementary files

Article information

Article type
Communication
Submitted
28 Mar 2026
Accepted
06 May 2026
First published
08 May 2026

Chem. Commun., 2026, Advance Article

A UiO-66-derived nano-separation microelectrode for in vivo dopamine sensing with high sensitivity and selectivity

L. Meng, C. Qing, Y. Wang, Y. Cai, H. Wei and M. Zhang, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D6CC01892K

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