Rational engineering of a highly sensitive and specific tyrosinase probe for guiding melanoma surgical resection

Abstract

Herein, a novel tyrosinase probe (SCy-tyr) was developed to overcome the limitations of poor selectivity and low activation efficiency, providing a new tool for precise imaging and surgical resection of melanoma.

Graphical abstract: Rational engineering of a highly sensitive and specific tyrosinase probe for guiding melanoma surgical resection

Supplementary files

Article information

Article type
Communication
Submitted
18 Mar 2026
Accepted
20 Apr 2026
First published
21 Apr 2026

Chem. Commun., 2026, Advance Article

Rational engineering of a highly sensitive and specific tyrosinase probe for guiding melanoma surgical resection

Y. Jian, Y. Luo, K. Li, M. Yang and X. Chen, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D6CC01628F

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