Preparation of covalent organic frameworks coated with cell membranes for precise analysis of cancer exosomes
Abstract
In this study, we have developed an electrochemical biosensor based on cell membrane-coated covalent organic frameworks for the selective detection of homologous exosomes. The biosensor can achieve a detection limit as low as 27 particles per µL. Moreover, it can effectively differentiate serum samples from patients with triple-negative breast cancer and luminal A breast cancer subtypes.
- This article is part of the themed collection: Chemistry for Global Health

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