From the journal:

Chemical Communications

Near-infrared fluorescence imaging of vimentin dynamics enables evaluation of stroke therapy in live mice

Xin Wang, ORCID logo †a   Simiao Zhang,†a   Xiwei Li,a   Qi Ding,a   Feida Che,a   Wen Zhang, ORCID logo a   Wei Wu*d  and  Ping Li ORCID logo *abc  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institutes of Biomedical Sciences, Shandong Normal University, Jinan 250014, People's Republic of China
E-mail: lip@sdnu.edu.cn

b College of Chemistry and Chemical Engineering, Key Laboratory of Water Security and Water Environment Protection in Plateau Intersection, Ministry of Education, Northwest Normal University, Lanzhou 730070, People's Republic of China

c Shandong University of Traditional Chinese Medicine, 655 Daxue Road, Jinan 250355, People's Republic of China

d Department of Neurology, Qi-Lu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, Shandong 250012, People's Republic of China
E-mail: drwuwei@126.com

Abstract

We design a novel near-infrared fluorescent probe, Vim-NIG. For the first time, Vim-NIG successfully visualized the spatiotemporal dynamics of vimentin in the brains of stroke mice.

Graphical abstract: Near-infrared fluorescence imaging of vimentin dynamics enables evaluation of stroke therapy in live mice

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Article information

DOI
https://doi.org/10.1039/D6CC00115G
Article type
Communication
Submitted
07 Jan 2026
Accepted
08 Feb 2026
First published
12 Feb 2026

Chem. Commun., 2026, Advance Article

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Near-infrared fluorescence imaging of vimentin dynamics enables evaluation of stroke therapy in live mice

X. Wang, S. Zhang, X. Li, Q. Ding, F. Che, W. Zhang, W. Wu and P. Li, Chem. Commun., 2026, Advance Article , DOI: 10.1039/D6CC00115G

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