A Pt@MOF-derived branch-leaf nanoarray: a mechanically flexible and high-performance biosensor for non-enzymatic electrochemical glucose detection

Abstract

Developing mechanically flexible nanoarray electrodes with strong catalytic performance is necessary for non-enzymatic glucose biosensing. Herein, we present a self-supported Pt@MOF-derived branch-leaf nanoarray that functions as an efficient electrode for non-enzymatic electrochemical glucose sensing. The as-prepared nanoarray electrode exhibits a wide linear detection range from 1 µM to 4 mM, and high sensitivities of 2866 and 518 µA mM⁻¹ cm⁻², while maintaining remarkable mechanical flexibility and long-term stability. In addition, the electrode enables reliable glucose detection in clinical serum and cell culture medium, validating its practical potential for biosensing applications.