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Correction: Dual-targeting hybrid nanoparticles for the delivery of SN38 to Her2 and CD44 overexpressed human gastric cancer

Zhe Yang a, Huiyan Luo ab, Zhong Cao a, Ya Chen a, Jinbiao Gao a, Yingqin Li a, Qing Jiang a, Ruihua Xu *b and Jie Liu *a
aDepartment of Biomedical Engineering, School of Engineering, Sun Yat-sen University, Guangzhou, Guangdong 510006, China. E-mail: liujie56@mail.sysu.edu.cn
bDepartment of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong 510060, China. E-mail: xurh@sysucc.org.cn

Received 22nd April 2025 , Accepted 22nd April 2025

First published on 2nd May 2025


Abstract

Correction for ‘Dual-targeting hybrid nanoparticles for the delivery of SN38 to Her2 and CD44 overexpressed human gastric cancer’ by Zhe Yang et al., Nanoscale, 2016, 8, 11543–11558, https://doi.org/10.1039/C6NR01749E.


The authors note the duplication of the 0.9% NaCl HER2 expression image in Fig. 8E in the panel intended to depict PLGA NPs HER2 expression in the original article. The authors now provide the correct PLGA NPs HER2 expression image here and confirm that this change does not affect the conclusions presented.
image file: d5nr90081f-f8.tif
Fig. 8 Anti-tumor growth effects of CPT-11 and SN38-loaded NPs with different formulations on nude mice bearing subcutaneous HGC27 tumors. Five groups were treated i.v. with 0.9% NaCl, CPT-11, SN38-loaded PLGA NPs, SN38-loaded HA-hybrid NPs and SN38-loaded AHNP/HA-hybrid NPs at the SN38 dose of 10 mg kg−1, respectively. The injection was repeated 5 times every 3 days. (A) The determination of tumor volume; (B) tumor morphology and size at the experimental end point (18th day); (C) tumor weight at the experimental end point (18th day); (D) the changes in the body weight of the nude mice during the 18 day experimental period. (E) H&E staining and immunohistochemistry analysis of tumor slices from mice on day 18 (scale bar: 100 μm). Data are given as mean ± SD (n = 4).

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