Open Access Article
This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported LicenceNanomedicine Revolutionizing Cancer Immunotherapy: Recent advancements in nanotechnological Strategies and Applications
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Jay Bhatt , Sweny Jain , Sharad Gupta and Dhiraj Devidas Bhatia
First published on 28th August 2025
Abstract
The convergence of nanotechnology and cancer immunotherapy represents a promising frontier in the fight against cancer, offering new avenues for enhancing therapeutic efficacy and specificity. This review delves into recent advancements in nanotechnological strategies and their applications within cancer immunotherapy. Key areas of focus include innovative approaches to tumor reduction through targeted drug delivery systems, the development of photoimmunotherapy techniques that combine light and immune activation for precise tumor eradication, and the modification of immune cells using nanoparticles to enhance their anti-tumor activity. Additionally, the surface modification of nanoparticles to induce immunogenic cell death (ICD) presents a novel method for amplifying immune responses against cancer. Finally, the integration of bioenzymes within nanomaterials offers a multifaceted approach to modulating the tumor microenvironment and improving immune responses. Collectively, these nanotechnological innovations hold the potential to overcome existing limitations in cancer immunotherapy, paving the way for more effective and personalized treatments.