A chalcone molecular switch with dual-state-emission for ratiometric tracking of hydrogen peroxide

Zhongyong Xu; Caiqiang Liao; Immanuel David Charles; Tianyi Qin; Bin Liu

doi:10.1039/D5CC04485E

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A chalcone molecular switch with dual-state-emission for ratiometric tracking of hydrogen peroxide

Zhongyong Xu,^a Caiqiang Liao,^b Immanuel David Charles,*^a Tianyi Qin

*^b and Bin Liu

*^a

Author affiliations

* Corresponding authors

^a College of Material Science and Engineering, Guangdong Provincial Key Laboratory of New Energy Materials Service Safety, Shenzhen University, Shenzhen 518060, P. R. China
E-mail: imanndavid@szu.edu.cn, bliu@szu.edu.cn

^b Key Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, One Health Institute, Hainan University, Haikou 570228, P. R. China
E-mail: qintianyi@hainanu.edu.cn

Abstract

A dual-state-emission fluorescent probe undergoes H₂O₂-triggered structural transformation, producing a distinct color change from yellow to red in both aqueous media and living cells.

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Article information

DOI: https://doi.org/10.1039/D5CC04485E
Article type: Communication
Submitted: 06 Aug 2025
Accepted: 04 Sep 2025
First published: 05 Sep 2025

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Chem. Commun., 2025, Advance Article

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A chalcone molecular switch with dual-state-emission for ratiometric tracking of hydrogen peroxide

Z. Xu, C. Liao, I. D. Charles, T. Qin and B. Liu, Chem. Commun., 2025, Advance Article , DOI: 10.1039/D5CC04485E

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A chalcone molecular switch with dual-state-emission for ratiometric tracking of hydrogen peroxide

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A chalcone molecular switch with dual-state-emission for ratiometric tracking of hydrogen peroxide

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